Bioactivity | Solidagonic acid inhibits HSET motor activity by promoting the conversion from abnormal monopolar to bipolar spindles. Solidagonic acid suppresses fission yeast cell death and enables reversion of the mitotic spindles from a monopolar to bipolar morphology. Solidagonic acid showed the growth inhibitory activity on the seedlings of Lactuca sativa L. and Lolium multiflorum Lam[1][2]. |
Name | Solidagonic acid |
CAS | 19941-91-4 |
Formula | C22H34O4 |
Molar Mass | 362.50 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Naoaki Kurisawa, et al. Kolavenic acid analog restores growth in HSET-overproducing fission yeast cells and multipolar mitosis in MDA-MB-231 human cells. Bioorg Med Chem. 2020 Jan 1;28(1):115154. [2]. Hisashi Kato-Noguchi, et al. Allelopathy and Allelochemicals of Solidago canadensis L. and S. altissima L. for Their Naturalization. Plants (Basel). 2022 Nov 25;11(23):3235. |