| Bioactivity | Sodium taurodeoxycholate hydrate, a bile acid, is an amphiphilic surfactant molecule synthesized from cholesterol in the liver. Sodium taurodeoxycholate hydrate activates the S1PR2 pathway in addition to the TGR5 pathway[1]. | ||||||||||||
| Invitro | The median plasma concentration of Taurodeoxycholate is 33.9 nM in healthy individuals[1].Taurodeoxycholate inhibits the binding of N-3H-methylscopolamine to the M3 muscarinic receptor of acetylcholine with an IC50 of 170 µM[1].Taurodeoxycholate (0.05-1.00 mM; 1-6 days) stimulates intestinal epithelial cell proliferation[2].Taurodeoxycholate (0.05-1.00 mM; 24 h) induces a significant increase in S-phase concentration and a significant decrease in G1-phase concentration of the cell cycle, increases c-myc protein and mRNA expression in IEC-6 cells[2]. Cell Proliferation Assay[2] Cell Line: | ||||||||||||
| Name | Sodium taurodeoxycholate hydrate | ||||||||||||
| CAS | 207737-97-1 | ||||||||||||
| Formula | C26H44NNaO6S | ||||||||||||
| Molar Mass | 521.69 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Sodium taurodeoxycholate hydrate
CAS: 207737-97-1 F: C26H44NNaO6S W: 521.69
Sodium taurodeoxycholate hydrate, a bile acid, is an amphiphilic surfactant molecule synthesized from cholesterol in the
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