| Bioactivity | Sirtuin modulator 4 (compound 12) is a sirtuin modulator. Sirtuin modulator 4 shows inhibitory effect to SIRT1 with an EC50 value of 51-100 μM. Sirtuin modulator 4 may be used for the research of increasing the lifespan of a cell, and preventing a wide variety of diseases and disorders including, for example, diabetes, obesity, neurodegenerative diseases, cardiovascular diseases, inflammation and cancer[1]. |
| Invitro | Sirtuin modulator 4 (0.7-100 μM) inhibits SIRT1 with an EC50 value of 51-100 μM[1]. |
| Name | Sirtuin modulator 4 |
| CAS | 327104-77-8 |
| Formula | C18H10N2O2S |
| Molar Mass | 318.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Milburn Michael, et al. Fused heterocyclic compounds and their use as sirtuin modulators. US7998974. 2011. |
Sirtuin modulator 4
CAS: 327104-77-8 F: C18H10N2O2S W: 318.35
Sirtuin modulator 4 (compound 12) is a sirtuin modulator. Sirtuin modulator 4 shows inhibitory effect to SIRT1 with an E
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