| Bioactivity | SirReal-1 is a potent and selective Sirt2 inhibitor（IC50 = 3.7 uM）[1]. |
| CAS | 801227-82-7 |
| Formula | C18H18N4OS2 |
| Molar Mass | 370.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Schiedel M, Rumpf T, Karaman B, et al. Structure-Based Development of an Affinity Probe for Sirtuin 2. Angew Chem Int Ed Engl. 2016;55(6):2252-2256. [2]. Rumpf T, Schiedel M, Karaman B, et al. Selective Sirt2 inhibition by ligand-induced rearrangement of the active site. Nat Commun. 2015;6:6263. |