| Bioactivity | Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2]. |
| Invitro | Silybin (0-200 mM; for 72 hours) has growth inhibition in a time- and dose-dependent manner[1]. Silybin (68 μM; for 72 hours) induces apoptosis and increases the cells in G1-phase of ~22%[1]. Silybin (68 μM; for 72 hours) induces AKT activity inhibition[1]. Cell Viability Assay[1] Cell Line: |
| Name | Silybin |
| CAS | 802918-57-6 |
| Formula | C25H22O10 |
| Molar Mass | 482.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |