Bioactivity | Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication[1]. |
Invitro | Silver sulfadiazine (AgSD) is a topical antibiotic used to the research of bacterial infection in burns[2]. |
Name | Silver sulfadiazine |
CAS | 22199-08-2 |
Formula | C10H9AgN4O2S |
Molar Mass | 357.14 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |