Sigma-1 receptor antagonist 2_product_DataBase

CAS: 1639220-15-7 F: C20H26ClN3O2 W: 375.89

Sigma-1 receptor antagonist 2 is a potent and selective sigma 1 receptor (σ1 R) antagonist with Kis of 3.88 and 1288 nM

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

Sigma-1 receptor antagonist 2 is a potent and selective sigma 1 receptor (σ1 R) antagonist with Kis of 3.88 and 1288 nM for σ1 and σ2 receptor, respectively[1].

Target

Ki: 3.88 nM (σ1 receptor), 1288 nM (σ2 receptor)

Name

Sigma-1 receptor antagonist 2

CAS

1639220-15-7

Formula

C20H26ClN3O2

Molar Mass

375.89

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Lan Y, et al. Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain. J Med Chem. 2014 Dec 26;57(24):10404-23.

PeptideDB

Sigma-1 receptor antagonist 2

CAS: 1639220-15-7 F: C20H26ClN3O2 W: 375.89