| Bioactivity | Sifuvirtide (SFT) acetate is a potent HIV fusion inhibitor. Sifuvirtide acetate inhibits HIV-1 mediated cell fusion in a dose-dependent manner and is highly potent against infection by primary and laboratory-adapted HIV-1 isolates of multiple genotypes. Sifuvirtide acetate can be used in the research of anti-HIV drugs[1]. | ||||||
| Sequence | Ac-Ser-Trp-Glu-Thr-Trp-Glu-Arg-Glu-Ile-Glu-Asn-Tyr-Thr-Arg-Gln-Ile-Tyr-Arg-Ile-Leu-Glu-Glu-Ser-Gln-Glu-Gln-Gln-Asp-Arg-Asn-Glu-Arg-Asp-Leu-Leu-Glu | ||||||
| Shortening | Ac-SWETWEREIENYTRQIYRILEESQEQQDRNERDLLE | ||||||
| Formula | C203H309N59O72.xC2H4O2 | ||||||
| Molar Mass | 4727.98 (free base) | ||||||
| Appearance | 固体 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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| Reference | [1]. Wang R R, et al. Sifuvirtide, a potent HIV fusion inhibitor peptide[J]. Biochemical and biophysical research communications, 2009, 382(3): 540-544. |
Sifuvirtide acetate
CAS: F: C203H309N59O72.xC2H4O2 W: 4727.98 (free base)
Sifuvirtide (SFT) acetate is a potent HIV fusion inhibitor. Sifuvirtide acetate inhibits HIV-1 mediated cell fusion in a
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