| Bioactivity | Si306 is a Src inhibitor with antitumor activity. Si306 reduces the phosphorylation of focal adhesion kinase (FAK) and the expression of epidermal growth factor receptor (EGFR), and inhibits the invasion of human glioblastoma (GBM)[1]. |
| CAS | 1640012-88-9 |
| Formula | C25H26BrClN6OS |
| Molar Mass | 573.94 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nešović, et al. "Src Inhibitors Pyrazolo [3, 4-d] pyrimidines, Si306 and Pro-Si306, inhibit focal adhesion kinase and suppress human glioblastoma invasion in vitro and in vivo." Cancers 12.6 (2020): 1570. |
Si306
CAS: 1640012-88-9 F: C25H26BrClN6OS W: 573.94
Si306 is a Src inhibitor with antitumor activity. Si306 reduces the phosphorylation of focal adhesion kinase (FAK) and t
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