| Bioactivity | Sevasemten is an allosteric inhibitor of skeletal muscle myosin. Sevasemten exhibits selectively myosin inhibition with IC50s of ≤10 μM (skeletal), >100 μM (cardiac), respectively[1][2]. |
| Name | Sevasemten |
| CAS | 2417395-15-2 |
| Formula | C16H11F4N5O2 |
| Molar Mass | 381.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russell Alan, et al. Preparation of substituted pyridazinones for use in the treatment of neuromuscular diseases: World Intellectual Property Organization, WO2021231615. 2021-11-18. [2]. WHO Drug Information-World Health Organization (WHO). |
Sevasemten
CAS: 2417395-15-2 F: C16H11F4N5O2 W: 381.28
Sevasemten is an allosteric inhibitor of skeletal muscle myosin. Sevasemten exhibits selectively myosin inhibition with
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