PeptideDB

Serotonin-d4 hydrochloride

CAS: 2469263-61-2 F: C10H9D4ClN2O W: 216.70

Serotonin-d4 (5-Hydroxytryptamine-d4) hydrochlorideis the deuterium labeledSerotonin (hydrochloride)(HY-B1473). Serotoni
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Serotonin-d4 (5-Hydroxytryptamine-d4) hydrochlorideis the deuterium labeledSerotonin (hydrochloride)(HY-B1473)[1]. Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM[2].
Invitro 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。
Name Serotonin-d4 hydrochloride
CAS 2469263-61-2
Formula C10H9D4ClN2O
Molar Mass 216.70
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.