Bioactivity | Seriniquinone, a selective anti-melanoma agent that targets Dermcidin, induces cell death by autophagocytosis. Seriniquinone is a metabolite produced by a rare marine bacterium of the genus Serinicoccus[1][2]. |
CAS | 22200-69-7 |
Formula | C20H8O4S |
Molar Mass | 344.34 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Lynnie Trzoss, et al. Seriniquinone, a selective anticancer agent, induces cell death by autophagocytosis, targeting the cancer-protective protein dermcidin. Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14687-92. [2]. Amanda S Hirata, et al. Seriniquinones as Therapeutic Leads for Treatment of BRAF and NRAS Mutant Melanomas. Molecules. 2021 Dec 4;26(23):7362. |