Bioactivity | Seratrodast(AA 2414) is an anti-asthmatic agent and a potent and selective thromboxane A2 receptor (TP) antagonist. | ||||||||||||
Name | Seratrodast | ||||||||||||
CAS | 112665-43-7 | ||||||||||||
Formula | C22H26O4 | ||||||||||||
Molar Mass | 354.44 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Ashida, Y., et al., A novel anti-asthmatic quinone derivative, AA-2414 with a potent antagonistic activity against a variety of spasmogenic prostanoids. Prostaglandins, 1989. 38(1): p. 91-112. [2]. Walsh, S.W., Y. Wang, and A. Killian, AA-2414, an antioxidant and thromboxane receptor blocker, completely inhibits peroxide-induced vasoconstriction in the human placenta. J Pharmacol Exp Ther, 1999. 290(1): p. 220-6. |