| Bioactivity | Senktide is a tachykinin NK3 receptor agonist. | ||||||
| Invitro | The selective NK3 receptor agonist Senktide excites 24 of 31 dopaminergic neurons in the substantia nigra pars compacta in a concentration-dependent manner. The effective concentration range is between 3 to 3000 nm. The mean EC50 for Senktide is 41.2±9 nm (n=5)[2]. | ||||||
| Name | Senktide | ||||||
| CAS | 106128-89-6 | ||||||
| Sequence | Suc-Asp-Phe-{Me-Phe}-Gly-Leu-Met-NH2 | ||||||
| Shortening | Suc-DF-{Me-Phe}-GLM-NH2 | ||||||
| Formula | C40H55N7O11S | ||||||
| Molar Mass | 841.97 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |