| Bioactivity | Semduramicin sodium (Pebac; D-Phenylalanyl-prolyl-arginyl Chloromethyl Ketone; D-Phe-Pro-Arg-CH2Cl) is an orally active anticoccidial agent with an IC50 value of 30.0 ng/mL for E. tenella. Semduramicin sodium reduces the lesions of E. aceroulina, E. brunetti and E. maxima. Semduramicin sodium (20-30 mg/kg) is well tolerates in broilers and possesses broad spectrum anticoccidial activity. Semduramicin sodium can be used in beef and poultry industry as coccidian inhibitor and growth promoter[1][2][3]. |
| CAS | 119068-77-8 |
| Formula | C45H75NaO16 |
| Molar Mass | 895.06 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Logan NB, at al. Anticoccidial efficacy of semduramicin. 2. Evaluation against field isolates including comparisons with salinomycin, maduramicin, and monensin in battery tests. Poult Sci. 1993 Nov;72(11):2058-63. [2]. Cao V, et al. Treatment of Lasalocid A, Salinomycin and Semduramicin as ionophore antibiotics in pharmaceutical wastewater by PAMAM-coated membranes[J]. Environmental Technology & Innovation, 2020, 20: 101103. [3]. Ricketts A P, et al. Anticoccidial efficacy of semduramicin in battery studies with laboratory isolates of coccidia[J]. Poultry science, 1992, 71(1): 98-103. |
Semduramicin sodium
CAS: 119068-77-8 F: C45H75NaO16 W: 895.06
Semduramicin sodium (Pebac; D-Phenylalanyl-prolyl-arginyl Chloromethyl Ketone; D-Phe-Pro-Arg-CH2Cl) is an orally active
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