| Bioactivity | Seglitide acetate (MK 678; L 36358 acetate) is a potent somatostatin receptor 2 (SSTR2) agonist and also a competitive antagonist of SSTR14, SSTR25, and SSTR28[1][2]. |
| CAS | 99248-33-6 |
| Sequence | Cyclo({Ala(Me)}-Tyr-{d-Trp}-Lys-Val-Phe) |
| Shortening | Cyclo({Ala(Me)}-Y-{d-Trp}-KVF) |
| Formula | C46H60N8O9 |
| Molar Mass | 869.02 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dimech J, et al. Antagonist effects of seglitide (MK 678) at somatostatin receptors in guinea-pig isolated right atria. Br J Pharmacol. 1993 Aug;109(4):898-9. [2]. Bhattarai J P, Kaszas A, Park S A, et al. Somatostatin inhibition of gonadotropin-releasing hormone neurons in female and male mice[J]. Endocrinology, 2010, 151(7): 3258-3266. |
Seglitide acetate
CAS: 99248-33-6 F: C46H60N8O9 W: 869.02
Seglitide acetate (MK 678; L 36358 acetate) is a potent somatostatin receptor 2 (SSTR2) agonist and also a competitive a
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