Bioactivity | Scutebarbatine X (Compound 2) is a neo-clerodane diterpenoids isolated from Scutellaria barbatae (Labiatae) and has anti-inflammatory properties[1]. |
Invitro | Scutebarbatine X 以剂量依赖性方式显著降低 LPS 刺激的 BV2 细胞产生 NO,IC50 值为 27.4 μM[1]。Scutebarbatine X (15, 30 μM;1 h) 剂量依赖性地降低 BV2 细胞中 iNOS 的表达[1]。Scutebarbatine X (7.5, 15, 30 μM; 24 h) 不会降低 BV2 细胞的活力[1]。 |
Name | Scutebarbatine X |
CAS | 1312716-26-9 |
Formula | C34H38N2O10 |
Molar Mass | 634.67 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Lee SR, et al. Constituents from Scutellaria barbata Inhibiting Nitric Oxide Production in LPS-Stimulated Microglial Cells. Chem Biodivers. 2017 Nov;14(11). |