| Bioactivity | Sclerotiorin is a reversible and uncompetitive inhibitor against soybean lipoxygenase-1 (LOX-1) (IC50: 4.2 μM). Sclerotiorin also shows antioxidant activity by scavenging free radical (ED50: 0.12 μM), and nonenzymatic lipid peroxidation inhibition activity. Sclerotiorin has antifungal activity, and also inhibits platelet aggregation. Sclerotiorin can be purified from the fermented broth of Penicillium frequentans[1][2]. |
| Invitro | Sclerotiorin (10 μM) 可在体外减缓 Aβ42 纤维形成 (使用 6E10 抗体检测)[2]。Sclerotiorin 对革兰氏阳性菌具有窄谱抗菌活性，MIC 范围为128-1028 μg/mL[3]。Sclerotiorin 在体外抑制胆固醇酯转移蛋白 (CETP) 活性 (IC50: 19.4 μM)[4]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Sclerotiorin 相关抗体: |
| CAS | 549-23-5 |
| Formula | C21H23ClO5 |
| Molar Mass | 390.86 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |