Bioactivity | Sclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB) cells and human leukemia cell lines. Sclareol induces cell apoptosis[1]. | ||||||||||||
Invitro | Sclareol is cytotoxic to 13 of 14 human leukemia cell lines tested, with IC50 values ranging from 6.0–24.2 μg/mL, but is not cytotoxic to peripheral blood mononuclear leukocytes within the same dose range[1]. | ||||||||||||
Name | Sclareol | ||||||||||||
CAS | 515-03-7 | ||||||||||||
Formula | C20H36O2 | ||||||||||||
Molar Mass | 308.50 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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