Bioactivity | Schnurri-3 inhibitor-1 is a potent schnurri-3 inhibitor which is an essential regulator of adult bone formation. Schnurri-3 inhibitor-1 can inhibit Shn3 with EF1alpha promoter in osteoblast cell line Shn3FFL with an AC50 value of 2.09 μM. Schnurri-3 inhibitor-1 can be used to research osteoporosis[1]. | |||||||||
Target | Schnurri-3 | |||||||||
Invitro | Schnurri-3 inhibitor-1 (0-50 μM; 24 h) can inhibit Shn3 with EF1alpha promoter in SV40 large T antigen-transformed osteoblast cell line (Clone20-Shn3FFL) with an AC50 value of 2.09 μM[1].Schnurri-3 inhibitor-1 (0.195-26 μM; 48 h) exhibits moderate activity in HepG2 mammalian cells with an AC50 value of 54.73 μM[1]. Cell Viability Assay[1] Cell Line: | |||||||||
Name | Schnurri-3 inhibitor-1 | |||||||||
CAS | 736154-60-2 | |||||||||
Formula | C12H10F2N2O2S | |||||||||
Molar Mass | 284.28 | |||||||||
Appearance | Solid | |||||||||
Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
Storage |
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Reference | [1]. National Center for Biotechnology Information. PubChem Compound Summary for CID 2473445. |