| Bioactivity | Salicylaldoxime is an organic compound, that has been used as a reagent for the gravimetric determination and separation of Cooper, Nickel, Palladium, Lead, Bismuth and Zine. The copper complex of Salicylaldoxime has anticancer activity[1][2]. |
| Invitro | Salicylaldoxime (300 μM) completely inhibits the relaxation activity of topoisomerase II when it forms a complex with copper; also inhibits L1210 leukaemia cell proliferation[1]. |
| Name | Salicylaldoxime |
| CAS | 94-67-7 |
| Formula | C7H7NO2 |
| Molar Mass | 137.14 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
| Reference | [1]. W Ligett and L Biefeld. Separation and Determination of Lead with Salicylaldoxime. Ind. Eng. Chem. Anal. Ed. 1941, 13, 11, 813-815. [2]. D. Jayaraju and Anand K. Kondapi. Anti-cancer copper salicylaldoxime complex inhibits topoisomerase II catalytic activity. Current Science. Vol. 81, No. 7 (10 October 2001), pp. 787-792 |