Bioactivity | Salbutamol (Albuterol) adipate is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol adipate promotes tumorigenesis of gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol adipate is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD)[1][2]. |
Invitro | Salbutamol (16 μM, 24 h) adipate 在胃癌细胞中通过 ERK (细胞外信号调节激酶) 磷酸化显著诱导 EMT、迁移和侵袭[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Salbutamol adipate 相关抗体: |
In Vivo | Salbutamol (5 mg/kg/day, 口服, 连续 2 周) adipate 可增加胃癌裸鼠的肿瘤生长能力[1]。Salbutamol (6 mg/kg, 口服, 连续 4 周) adipate 对 STZ (HY-13753) 诱导的糖尿病大鼠骨骼肌萎缩具有显著的保护作用[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
CAS | 149234-08-2 |
Formula | C13H21NO3.1/2C6H10O4 |
Molar Mass | 312.38 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Lu Y, et al. Chronic stress model simulated by salbutamol promotes tumorigenesis of gastric cancer cells through β2-AR/ERK/EMT pathway. J Cancer. 2022 Jan 1;13(2):401-412. [2]. Hong YP, et al. Effects of Castanospermine on Inflammatory Response in a Rat Model of Experimental Severe Acute Pancreatitis. Arch Med Res. 2016 Aug;47(6):436-445. |