Bioactivity | Sacubitril (sodium) (Standard) is the analytical standard of Sacubitril (sodium). This product is intended for research and analytical applications. Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19. |
CAS | 149690-05-1 |
Formula | C24H28NNaO5 |
Molar Mass | 433.47 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |