| Bioactivity | SYM 2081 is a high-affinity ligand and potent, selective agonist of kainate receptors, inhibits [3H]-kainate binding with an IC50 of 35 nM, almost 3000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively[1]. | ||||||||||||
| Target | IC50: 35 nM (kainate receptors) | ||||||||||||
| Name | SYM 2081 | ||||||||||||
| CAS | 31137-74-3 | ||||||||||||
| Formula | C6H11NO4 | ||||||||||||
| Molar Mass | 161.16 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Lee JY, et al. Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction. Comp Biochem Physiol C Toxicol Pharmacol. 2009 Nov;150(4):546-57. |