Bioactivity | SW116 free base is a selective fluorescent ligand for sigma-2 receptor with a Ki of 14 nM. SW116 free base exhibits in methanol a maximal excitation wavelength of 333 nM, and a maximal emission wavelength of 506 nM. SW116 free base can be internalized into MDA-MB-435 cells, and reach 50% maximum fluorescent intensity in 24 minutes. SW116 free base can be as a fluorescent probe used in cancer research[1]. |
CAS | 1036759-00-8 |
Formula | C39H56N4O5S |
Molar Mass | 692.95 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zeng C, et al. Characterization and evaluation of two novel fluorescent sigma-2 receptor ligands as proliferation probes[J]. Molecular imaging, 2011, 10(6): 7290.2011. 00009. |