Bioactivity | SUCNR1-IN-1 (Compound 20) is a SUCNR1 inhibitor (IC50: 88 nM for hSUCNR1). SUCNR1-IN-1 can be used for research of rheumatoid arthritis, liver fibrosis, or obesity[1]. |
Name | SUCNR1-IN-1 |
CAS | 2711753-52-3 |
Formula | C26H22ClF3N2O4 |
Molar Mass | 518.91 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Velcicky J, et al. Discovery and Optimization of Novel SUCNR1 Inhibitors: Design of Zwitterionic Derivatives with a Salt Bridge for the Improvement of Oral Exposure. J Med Chem. 2020 Sep 10;63(17):9856-9875. |