| Bioactivity | STM2457 is a first-in-class, highly potent, selective and orally active METTL3 inhibitor with an IC50 of 16.9 nM. STM2457 can be used for the research of acute myeloid leukaemia (AML)[1][2]. | ||||||||||||
| Invitro | STM2457 (Compound 72) inhibits MOLM13 cells proliferation with an IC50 of 8.699 μM[1]. | ||||||||||||
| Name | STM2457 | ||||||||||||
| CAS | 2499663-01-1 | ||||||||||||
| Formula | C25H28N6O2 | ||||||||||||
| Molar Mass | 444.53 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|