| Bioactivity | STING modulator-5 (compound 38) is a STING modulator with a pIC50 value of 9.5. STING modulator-5 antagonizes peripheral blood mononuclear cells (PBMC) with a pIC50 value of 8.1. STING modulator-5 is a antagonist of THP-1 cells, it can be used for immunological disease research[1]. |
| Invitro | STING modulator-5 (4小时) 对外周血单核细胞 (PBMC) 有拮抗作用，pIC50 值为 8.1[1]。STING modulator-5 对人 STING 的 C 端结构域 (CTD) 具有结合效力，通过 FRET 检测的 pIC50 值为 9.5[1]。STING modulator-5 拮抗 THP-1 细胞的 pIC50 值为 8.9[1]。 |
| Name | STING modulator-5 |
| CAS | 2305940-22-9 |
| Formula | C43H45F4N11O5 |
| Molar Mass | 871.88 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fosbenner, David T, et al. Modulators of stimulator of interferon genes. WO 2019/069270 Al. 2022. |
STING modulator-5
CAS: 2305940-22-9 F: C43H45F4N11O5 W: 871.88
STING modulator-5 (compound 38) is a STING modulator with a pIC50 value of 9.5. STING modulator-5 antagonizes peripheral
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.