| Bioactivity | STING ligand-1 is a lead STING ligand with an IC50 of 68 nM for HAQ STING[1]. | ||||||||||||
| Target | IC50: 68 nM (HAQ STING) | ||||||||||||
| Invitro | STING ligand-1 (Compound 18) exhibits functional inhibition of STING mediated cytokine release[1]. | ||||||||||||
| Name | STING ligand-1 | ||||||||||||
| CAS | 2365039-41-2 | ||||||||||||
| Formula | C29H27ClFNO5 | ||||||||||||
| Molar Mass | 523.98 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Siu T, et al. Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING. ACS Med Chem Lett. 2018 Dec 6;10(1):92-97. |