| Bioactivity | STING agonist-22 (CF501) is a potent non-nucleotide STING agonist. STING agonist-22 is a adjuvant by activating STING to induce the type I interferon (IFN-I) response and proinflammatory cytokine production. STING agonist-22 can be used as an adjuvant to boost the original protein vaccine, producing potent, broad, and long-term immune protection. STING agonist-22 can be used for SARS-CoV-2 variants and sarbecovirus diseases research[1]. |
| Invitro | STING agonist-22 (CF501) 导致 THP-1 细胞中先天免疫反应的快速和强烈激活[1]。 |
| In Vivo | STING agonist-22 (CF501) 以可接受的安全性在小鼠中稳健但短暂地激活先天免疫[1]。 Animal Model: |
| Name | STING agonist-22 |
| CAS | 2408723-12-4 |
| Formula | C40H48N14O6 |
| Molar Mass | 820.90 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Liu Z, et al. A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice, rabbits and NHPs. Cell Res. 2022 Mar;32(3):269-287. |
STING agonist-22
CAS: 2408723-12-4 F: C40H48N14O6 W: 820.90
STING agonist-22 (CF501) is a potent non-nucleotide STING agonist. STING agonist-22 is a adjuvant by activating STING to
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.