| Bioactivity | STING-IN-10 (P8) is a dual STING degrader and inhibitor with aDC50 value of 2.58 μM in THP-1 cells. STING-IN-10 has anti-inflammatory activity[1]. |
| Formula | C35H33N7O11 |
| Molar Mass | 727.68 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xue L, Liu R, Zhang L, Qiu T, Liu L, Yin R, Jiang T. Discovery of novel nitrofuran PROTAC-like compounds as dual inhibitors and degraders targeting STING. Eur J Med Chem. 2024 Dec 5;279:116883. |