Bioactivity | STING Degrader-1 (compound 2) is a potent STING degrader that covalently binds to STING and E3 ligase. STING Degrader-1 induces STING degradation through a ubiquitin-proteasome system-dependent pathway[1]. |
Formula | C26H24N4O7 |
Molar Mass | 504.49 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Miki Nakamura, et al. Development of STING degrader with double covalent ligands. Bioorg Med Chem Lett. 2024 Feb 24:102:129677. |