| Bioactivity | STE-MEK1(13) (Ste-MPKKKPTPIQLNP-NH?) is a cell permeable ERK1/2 inhibitor (IC50: 13-30?μM). STE-MEK1(13) inhibits ERK1/2 phosphorylation[1][2]. |
| Target | 13-30?μM (ERK1/2) |
| Name | STE-MEK1(13) |
| CAS | 566872-15-9 |
| Sequence | {Ste}-Met-Pro-Lys-Lys-Lys-Pro-Thr-Pro-Ile-Gln-Leu-Asn-Pro-NH2 |
| Shortening | {Ste}-MPKKKPTPIQLNP-NH2 |
| Formula | C86H153N19O17S |
| Molar Mass | 1757.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li G, et al. A novel cellular survival factor--the B2 subunit of vacuolar H+-ATPase inhibits apoptosis. Cell Death Differ. 2006 Dec;13(12):2109-17. [2]. Whiteman M, et al. Peroxynitrite-modified collagen-II induces p38/ERK and NF-kappaB-dependent synthesis of prostaglandin E2 and nitric oxide in chondrogenically differentiated mesenchymal progenitor cells. Osteoarthritis Cartilage. 2006 May;14(5):460-70. |
STE-MEK1(13)
CAS: 566872-15-9 F: C86H153N19O17S W: 1757.32
STE-MEK1(13) (Ste-MPKKKPTPIQLNP-NH?) is a cell permeable ERK1/2 inhibitor (IC50: 13-30?μM). STE-MEK1(13) inhibits ERK1/
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