| Bioactivity | STAT3-IN-35 is a STAT3 inhibitor that binds to SH2 domain. STAT3-IN-35 inhibits the phosphorylation of STAT3 and possesses antiproliferative activities against triple-negative breast cancer (TNBC) cell lines. STAT3-IN-35 also has a toxicity and potent antitumor activity in a TNBC xenograft model[1]. |
| CAS | 2849535-96-0 |
| Formula | C21H23NO4 |
| Molar Mass | 353.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fan C, et al. Natural Product-Inspired Discovery of Naphthoquinone-Furo-Piperidine Derivatives as Novel STAT3 Inhibitors for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2024 Sep 12;67(17):15291-15310. |
STAT3-IN-35
CAS: 2849535-96-0 F: C21H23NO4 W: 353.41
STAT3-IN-35 is a STAT3 inhibitor that binds to SH2 domain. STAT3-IN-35 inhibits the phosphorylation of STAT3 and possess
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.