| Bioactivity | ST7710AA1 (compound 1l) is a potent PARP-1 inhibitor with an IC50 value of 0.07 µM. ST7710AA1 shows an antiproliferative activity. ST7710AA1 shows anticancer activity[1]. |
| Invitro | ST7710AA1 (compound 1l) (0-200 µM; 72 h) 表现出抗增殖作用，对 HCC1937、Capan 1 细胞的 IC50s 分别为 19.43、22.04 µM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> ST7710AA1 相关抗体: |
| In Vivo | ST7710AA1 (100 mg/kg; i.p.; every 2 days for 2 weeks) 在小鼠中显示出抗肿瘤活性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| CAS | 1542067-20-8 |
| Formula | C20H22N4O |
| Molar Mass | 334.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cincinelli R, et al. 7-Azaindole-1-carboxamides as a new class of PARP-1 inhibitors. Bioorg Med Chem. 2014 Feb 1;22(3):1089-103. |