| Bioactivity | ST 198 is an orally active D3R antagonist. ST 198 can block the expression of nicotine-induced CPP at doses selective for D3R. ST 198 can be used for the research of neurological disease[1]. |
| Invitro | ST 198 可以在对 D3R 具有选择性的剂量下阻断尼古丁诱导的 CPP 的表达[1]。 |
| In Vivo | ST 198 (p.o.; 3, 30, 100 mg/kg) 抑制尼古丁 CPPs 的表达[1]。 Animal Model: |
| Name | ST 198 |
| CAS | 854924-64-4 |
| Formula | C22H26N2O |
| Molar Mass | 334.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Le Foll B, et al. Dopamine D3 receptor ligands block nicotine-induced conditioned place preferences through a mechanism that does not involve discriminative-stimulus or antidepressant-like effects. Neuropsychopharmacology. 2005;30(4):720-730. |