| Bioactivity | SS148 is a dual inhibitor of nsp14/nsp16 MTase. SS148 significant inhibits nsp10–nsp16 with an IC50 of 1.2 μM[1][2]. |
| Name | SS148 |
| CAS | 1985669-27-9 |
| Formula | C16H20N6O5S |
| Molar Mass | 408.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nigam A, et al. Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors. bioRxiv [Preprint]. 2023 Nov 13:2023.10.03.560722. [2]. Klima M, et al. Crystal structure of SARS-CoV-2 nsp10-nsp16 in complex with small molecule inhibitors, SS148 and WZ16. Protein Sci. 2022 Sep;31(9):e4395. |