| Bioactivity | SPV106 is histone acetylase (HAT) and GCN5-related N-acetyltransferases (GNAT) activator. SPV106 can be used for the research of type 2 diabetes (T2D)[1]. |
| Invitro | SPV106 恢复正常水平的 H3K9Ac 和 H3K14Ac，降低 DNA CpG 高甲基化，恢复 D-CMSC 增殖和分化[1]。SPV106 (5 µmol/L) 在 D-CMSC[1] 中减少细胞衰老并诱导 cKit 表达[1]。 Western Blot Analysis[1] Cell Line: |
| Name | SPV106 |
| CAS | 1036939-38-4 |
| Formula | C22H40O4 |
| Molar Mass | 368.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Matteo Vecellio, et al. The histone acetylase activator pentadecylidenemalonate 1b rescues proliferation and differentiation in the human cardiac mesenchymal cells of type 2 diabetic patients. Diabetes. 2014 Jun;63(6):2132-47. |
SPV106
CAS: 1036939-38-4 F: C22H40O4 W: 368.55
SPV106 is histone acetylase (HAT) and GCN5-related N-acetyltransferases (GNAT) activator. SPV106 can be used for the res
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This product is for research use only, not for human use. We do not sell to patients.