| Bioactivity | SPSB2-iNOS inhibitory cyclic peptide-2 (Compound CP2) is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 21 nM. SPSB2-iNOS inhibitory cyclic peptide-2 is reduction-resistant and oxidatively stable[1]. |
| CAS | 1989528-33-7 |
| Sequence | cyclo{Trp-Asp-Ile-Asn-Asn-Asn-βAla} |
| Shortening | cyclo{WDINNN-βAla} |
| Formula | C36H49N11O12 |
| Molar Mass | 827.84 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yap BK, et al., Redox-stable cyclic peptide inhibitors of the SPSB2-iNOS interaction. FEBS Lett. 2016 Mar;590(6):696-704. |
SPSB2-iNOS inhibitory cyclic peptide-2
CAS: 1989528-33-7 F: C36H49N11O12 W: 827.84
SPSB2-iNOS inhibitory cyclic peptide-2 (Compound CP2) is an inhibitor for the interaction of SPRY domain and SOCS-box pr
Data collection：peptidedb@qq.com
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