PeptideDB

SPSB2-iNOS inhibitory cyclic peptide-2

CAS: 1989528-33-7 F: C36H49N11O12 W: 827.84

SPSB2-iNOS inhibitory cyclic peptide-2 (Compound CP2) is an inhibitor for the interaction of SPRY domain and SOCS-box pr
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Bioactivity SPSB2-iNOS inhibitory cyclic peptide-2 (Compound CP2) is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 21 nM. SPSB2-iNOS inhibitory cyclic peptide-2 is reduction-resistant and oxidatively stable[1].
CAS 1989528-33-7
Sequence cyclo{Trp-Asp-Ile-Asn-Asn-Asn-βAla}
Shortening cyclo{WDINNN-βAla}
Formula C36H49N11O12
Molar Mass 827.84
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Yap BK, et al., Redox-stable cyclic peptide inhibitors of the SPSB2-iNOS interaction. FEBS Lett. 2016 Mar;590(6):696-704.