| Bioactivity | SPR38 is a potent SARS-CoV-2 main protease inhibitor, with a Ki of 0.260 μM. SPR38 also inhibits hCatL and hCatB, with Ki values of 1.92 μM and 11.1 μM, respectively[1]. |
| Invitro | SPR38 在 100 μM 时对 SARS-CoV-2 木瓜蛋白酶样蛋白酶 (PLpro) 没有抑制作用，PLpro 在处理病毒多蛋白中起着至关重要的作用[1]。 |
| Name | SPR38 |
| Formula | C24H33N3O5 |
| Molar Mass | 443.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Previti S, et al. Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors. |