| Bioactivity | SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor, with an IC50 of 9 nM[1]. |
| Target | IC50: 9 nM (SPPL2a). |
| Name | SPL-410 |
| CAS | 2351886-00-3 |
| Formula | C24H31F3N2O4S |
| Molar Mass | 500.57 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, stored under nitrogen, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture) |
| Reference | [1]. Velcicky J, et al. Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors. ACS Med Chem Lett. 2019 May 23;10(6):887-892. |
SPL-410
CAS: 2351886-00-3 F: C24H31F3N2O4S W: 500.57
SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2
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