| Bioactivity | SPAA-52 is an orally active, competitive and reversible low-molecular-weight protein tyrosine phosphatase (LMW-PTP) inhibitor (IC50=4 nM, Ki=1.2 nM). SPAA-52 can be used in diabete research[1]. |
| Target | IC50: 4 nM (LMW-PTP) |
| In Vivo | 1.19Plasma PK Parameters in Healthy Mice[1] Compound |
| Name | SPAA-52 |
| Formula | C8H8Br2N2O4S |
| Molar Mass | 388.03 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. He R, et al. Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors. J Med Chem. 2022 Oct 5. |