Bioactivity | SOS1 Ligand intermediate-7 (65) is an intermediate for the synthesis of SOS1 ligand (HY-111671). SOS1 activator 1 (HY-111671) can be used for the synthesis of PROTAC SOS1 degrader-1 (HY-145737)[1]. |
CAS | 2836274-66-7 |
Formula | C19H19F3N4O2 |
Molar Mass | 392.37 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Yan Lv, et al/ A Potent SOS1 PROTAC Degrader with Synergistic Efficacy in Combination with KRASG12C Inhibitor. J Med Chem. 2024 Feb 22;67(4):2487-2511. |