| Bioactivity | SOD1 (147-153) human is a peptide fragment of Cu/Zn superoxide dismutase (SOD1) with a high propensity to form amyloid fibrils. SOD1 (147-153) human may trigger the aggregation of full-length SOD1 and is a common molecular determinant of familial amyotrophic lateral sclerosis (fALS) and sporadic amyotrophic lateral sclerosis (sALS)[1]. |
| CAS | 2760733-01-3 |
| Sequence | Gly-Val-Ile-Gly-Ile-Ala-Gln |
| Shortening | GVIGIAQ |
| Formula | C29H52N8O9 |
| Molar Mass | 656.77 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ivanova, et al. "Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS." Proceedings of the National Academy of Sciences 111.1 (2014): 197-201. |
SOD1 (147-153) human
CAS: 2760733-01-3 F: C29H52N8O9 W: 656.77
SOD1 (147-153) human is a peptide fragment of Cu/Zn superoxide dismutase (SOD1) with a high propensity to form amyloid f
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