| Bioactivity | SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis[1][2]. | |||||||||
| Name | SN38-COOH | |||||||||
| CAS | 2170118-23-5 | |||||||||
| Formula | C26H24N2O8 | |||||||||
| Molar Mass | 492.48 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
|
|||||||||
| Reference | [1]. Wilson Lim, et al. Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma. PLoS Negl Trop Dis. 2018 Apr 26;12(4):e0006437. [2]. Wallin A, et al. Anticancer effect of SN-38 on colon cancer cell lines with different metastatic potential. Oncol Rep. 2008 Jun;19(6):1493-8. |
SN38-COOH
CAS: 2170118-23-5 F: C26H24N2O8 W: 492.48
SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomera
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.