| Bioactivity | SMO-IN-5 ((Compound 25(B31)) is a potent smoothened (SMO) inhibitor that inhibits Hedgehog (Hh) signaling. SMO-IN-5 can inhibit cell proliferation and induce Apoptosis. SMO-IN-5 has antitumor activity[1]. |
| Formula | C25H24N6O |
| Molar Mass | 424.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li H, et al. Synthesis of pyridyl pyrimidine hedgehog signaling pathway inhibitors and their antitumor activity in human pancreatic cancer. Eur J Med Chem. 2024 Oct 15;280:116961. |