| Bioactivity | SMIP34 is a PELP1 inhibitor. SMIP34 reduces cell viability and colony formation. SMIP34 induces apoptosis and cell cycle arrest at S phase. SMIP34 decreases the expression of PELP1. SMIP34 shows antitumor activity. SMIP34 has the potential for the research of triple-negative breast cancer (TNBC)[1]. |
| Target | PELP1 |
| CAS | 946262-80-2 |
| Formula | C20H15ClFN5O2S |
| Molar Mass | 443.88 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Altwegg KA, et al. Targeting PELP1 oncogenic signaling in TNBC with the small molecule inhibitor SMIP34. Breast Cancer Res Treat. 2023 Jul;200(1):151-162. |
SMIP34
CAS: 946262-80-2 F: C20H15ClFN5O2S W: 443.88
SMIP34 is a PELP1 inhibitor. SMIP34 reduces cell viability and colony formation. SMIP34 induces apoptosis and cell cycle
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