Bioactivity | SMCY peptide inhibits the binding of iodinated standard peptide to HLA-B7 with an IC50 of 34 nM. As an epitope of the H-Y antigen, SMCY peptide can be presented by the HLA-B7 molecule and recognized by specific T cells, leading to transplant rejection[1]. |
CAS | 169312-12-3 |
Sequence | Ser-Pro-Ser-Val-Asp-Lys-Ala-Arg-Ala-Glu-Leu |
Shortening | SPSVDKARAEL |
Formula | C49H85N15O18 |
Molar Mass | 1172.29 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wang W, et al. Human H-Y: a male-specific histocompatibility antigen derived from the SMCY protein. Science. 1995 Sep 15;269(5230):1588-90. |