Bioactivity | SMARCA-BD ligand 1 hydrochloride for Protac is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC[1]. |
Target | SMARCA2 |
Name | SMARCA-BD ligand 1 for Protac hydrochloride |
CAS | 2380272-56-8 |
Formula | C14H18ClN5O |
Molar Mass | 307.78 |
Appearance | 固体 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Reference | [1]. Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680. |