PeptideDB

SMARCA-BD ligand 1 for Protac hydrochloride

CAS: 2380272-56-8 F: C14H18ClN5O W: 307.78

SMARCA-BD ligand 1 hydrochloride for Protac is a compound that binds to the BAF ATPase subunits SMARCA2, and used for de
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Bioactivity SMARCA-BD ligand 1 hydrochloride for Protac is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC[1].
Target SMARCA2
Name SMARCA-BD ligand 1 for Protac hydrochloride
CAS 2380272-56-8
Formula C14H18ClN5O
Molar Mass 307.78
Appearance 固体
Transport Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Reference [1]. Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.