| Bioactivity | SMAPP1 is an activator of protein phosphatase-1 (PP1). SMAPP1 increases phosphorylation of CDK9’s Ser90 and Thr186 residues, but not Ser175. SMAPP1 induces HIV-1 replication, upregulates HIV-1 transcription that led to the reactivation of latent HIV-1 provirus[1]. |
| CAS | 327081-00-5 |
| Formula | C27H25N5O5S2 |
| Molar Mass | 563.65 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ammosova T, et al. Protein Phosphatase-1 Regulates Expression of Neuregulin-1. Biology (Basel). 2016 Dec 2;5(4):49. |